@article{ajmr20241231,
author={{Michel, Toukam and Arnaud, Mbanzouen William and Rosanne, Ngome Minone and Suzanne, Belinga and Larissa, Tagne and Pierrette, Simo and Esther, Sokeng and Marcelle, Abanda and Urbaine, Ngon and Laurence, Noubissi-Jouegouo and Manuella, Ango and Harley, Ndamukong and Romain, Mbe Jean and Flaubert, Tassadjo and Thierry, Fouda and Edvige, Biloa and Dimitri, Ngongang and Ariane, Nzouankeu and Emilia, Lyonga Mbamyah},
title={Awareness on the Evolving of Bacterial Resistance Bacteria Isolated in Joint Fluids Received at the Centre Pasteur Du Cameroun from 2016 To 2021},
journal={American Journal of Microbiological Research},
volume={12},
number={3},
pages={38--44},
year={2024},
url={https://pubs.sciepub.com/ajmr/12/3/1},
issn={2328-4137},
abstract={<b>Introduction: </b>Septic arthritis is a serious medical emergency because of the morbidity and functional risks it entails. Variations in the microbiological profile and the emergence of antimicrobial resistance remain a challenge. This study was undertaken to determine the bacterial aetiologies of septic arthritis and their antimicrobial resistance trends, in order to update data and contribute to better therapeutic management of patients suffering from this pathology. <b>Methods: </b>A retrospective and prospective study was carried out on joint fluids received at the Centre Pasteur du Cameroun Laboratory between 2016 and 2021. Cytobacteriological analysis was performed on these joint fluids according to the medical microbiology guidelines. <b>Results: </b>471 joint fluids were received and tested, of which 83 (17.6%) were culture positive. The main bacteria isolated were <i>Staphylococcus aureus</i> (n=33; 38.8%) followed by <i>Streptococcus pneumoniae</i> (n=5; 5.9%), <i>Klebsiella pneumoniae</i> (n=5; 5.9%) and <i>Streptococcus pyogenes</i> (n=4; 4.7%). Vancomycin, teicoplanin, linezolid and nitrofuran were 100% active on gram-positive cocci, while imipenem and amikacin were active on gram-negative bacteria, with sensitivity frequencies of 92.3% and 80.8% respectively. We also observed a significant upward trend in the frequency of isolation of MDR bacteria from joint fluids during the study period. <b>Conclusion: </b>Although the frequency of joint fluid infections is not very high, there is still a predominance of staphylococcus aureus. We therefore suggest combining these antibiotics during empirical treatment until definitive culture results are available},
doi={10.12691/ajmr-12-3-1}
publisher={Science and Education Publishing}
}