eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2025-12-28 13 12 88 90 10.12691/ajmcr-13-12-2 AJMCR202513122 article Nada Barkia 1 Khouloud Mnif mnif_khouloud@medecinesfax.org 1 Hana Chaabouni 1 Yoldez Ben Jemaa 2 Tarak Ben Jemaa 2 Amira Trigui 2 Mounir Ben Jemaa 2 Infectious diseases department.Hedi Chaker Hospital, Sfax, Tunisia Ophtalmology Department. Habib Bourguiba Hospital, Sfax, Tunisia Kocuria (K) kristinae is a rare pathogen, with only a few reported cases, predominantly in immunocompromised patients and occasionally in immunocompetent individuals. This report presents a case of K.kristinae meningoencephalitis in 34-year-old man undergoing neurosurgery for a type 1 Arnold Chiari malformation with a ventriculoperitoneal shunt. The patient developed fever and epileptic seizures, prompting an etiological investigation, including lumbar puncture and the CSF was clear, 140 leukocytes/mL with 40% neutrophil polynuclear and 60% lymphocyte, increased proteinorachy to 0.61g/L and hypoglucorachy to 0.59 mmol/L, with a positive culture for K. Kristinae. The patient received 45 days of antibiotic therapy with meropenem and vancomycin.Despite treatment, the patient succumbed to progressive neurological deterioration. https://pubs.sciepub.com/ajmcr/13/12/2/ajmcr-13-12-2.pdf Kocuria kristinae meningoencephalitis rare