eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2024-09-12 12 9 134 137 10.12691/ajmcr-12-9-1 AJMCR20241291 article H¨¹seyin D?ngelli drhuseyindongelli@gmail.com 1 Sevgi Kara 1 Bet¨¹l Kurumluo?lugil 1 Mesut Akarsu 2 Department of Internal Medicine, Dokuz Eylul University Hospital, Izmir, Turkiye, 35330 Department of Gastroenterology, Dokuz Eylul University Hospital, Izmir, Turkiye, 35330 Boerhaave Syndrome is a spontaneous rupture of the esophagus due to repeated vomiting and has a high mortality rate. Multiple endocrine neoplasia(MEN) syndromes are autosomal dominant disorders that can develop tumors in endocrine glands. A male patient in his 40s was admitted to the emergency room with complaints of chronic diarrhea and nausea. The patient was hospitalized in the gastroenterology department with a preliminary diagnosis of acute pancreatitis which was excluded later. On the first day of hospitalization, the patient developed dyspnea with desaturation after repeated retching. Thoracoabdominal CT revealed massive pleural effusion on the right side. Therefore, a chest tube was inserted. Six-hour later, he became hypotensive and a chest X-ray revealed a left-sided pneumothorax. A second chest tube was inserted. He was diagnosed with Boerhaave Syndrome by esophagography. Metallic stent was placed in the ruptured site.He eventually died of sepsis due to mediastinitis due to Boerhaave¡¯s syndrome. https://pubs.sciepub.com/ajmcr/12/9/1/ajmcr-12-9-1.pdf Boerhaave¡¯s Syndrome Dieulafoy's lesion MEN Syndrome pneumothorax Zollinger-Ellison Syndrome