eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2024-07-28 12 7 103 109 10.12691/ajmcr-12-7-4 AJMCR20241274 article Shabir A Shah 1 Nadeem Yunus 2 Nishant Gaba 3 Noopur Rathi nupurrathi11@gmail.com 4 Department of Prosthodontics, Government dental college and hospital, University of Kashmir, Jammu and Kashmir, India Department of Prosthodontics, Faculty of dentistry, Jamia Millia Institute, JMIU, New Delhi, India Department of Maxillofacial prosthodontics, Inderprastha Dental College & Hospital, CCSU, UP, India Department of Prosthodontics, DJ College of dental sciences, BRAU, Uttar Pradesh, India Maxillofacial prosthesis (MFP) is a customised prosthesis; therefore, one requires a blend of multiple skills in individualising them for a specific patient. Retention of these prostheses largely depends on available hard and soft tissues, based on which the retention aids can be either mechanical or chemical. Most extraoral prostheses, irrespective of mechanical retention, cannot adhere to the skin for which chemical adhesives are used. While most of the published research focuses on materials, this review has been aimed at collecting evidence-based information on the technical aspects of both mechanical and chemical aids used to retain different types of MFP. Four medical databases were searched for relevant research articles using relevant terms in combination with Boolean operators. The search produced 137 research articles, and after careful evaluation of the articles, about 79 research articles fulfilled the criteria for this review. The technical considerations for the mechanical and chemical aids were further searched from relevant manufacturer catalogues. The review provides a comprehensive clinically oriented background of both in terms of clinical application. https://pubs.sciepub.com/ajmcr/12/7/4/ajmcr-12-7-4.pdf oral cancers maxillofacial prosthesis maxillectomy hemi mandibulectomy maxillofacial implants