eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2024-07-21 12 7 101 102 10.12691/ajmcr-12-7-3 AJMCR20241273 article Chihiro Maekawa 1 Tatsuro Sakai 1 Hiroaki Taniguchi 1 Noriko Tanaka 1 Youichi Yanagawa yyanaga@juntendo.ac.jp 1 Department of Acute Critical Care Medicine, Juntendo Shizuoka Hospital, Izunokuni, Japan A 31-year-old male with no medical history, who runs his own nightclub, experienced altered consciousness after heavy alcohol drinking and was transported to our hospital by ambulance. On arrival, he was in a deep coma with tongue base retraction and snoring respiration. Auscultation revealed wet rales in both lung fields, necessitating tracheal intubation. Whole-body computed tomography revealed left-dominant ground-glass opacities and infiltrative shadows in both lungs' dorsal regions. His heart function was normal. The patient was diagnosed with acute alcohol intoxication, bilateral pulmonary edema, and aspiration. His lung function improved without event, and he was discharged on the third day. This case showed rare pulmonary edema induced by acute alcohol intoxication. The mechanism of pulmonary edema might be due to impaired alveolar epithelium and alveolar macrophages, reduction in alveolar fluid clearance, fluid retention in the human body due to the direct effect of alcohol, and/or negative-pressure pulmonary edema caused by airway obstruction due to coma. https://pubs.sciepub.com/ajmcr/12/7/3/ajmcr-12-7-3.pdf alcohol pulmonary edema negative pressure