eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2024-05-12 12 5 81 84 10.12691/ajmcr-12-5-4 AJMCR20241254 article Rasim Bakhtiyar Bayramov 1 Khayala Ismayil Ismayilzada xeyale_ismayilzade@yahoo.com 2 Sayyara Dunyamali Huseynova 3 Chief of Diagnostic Radiology Department, Educational-Surgical Clinic of Azerbaijan Medical University, Baku, Azerbaijan Diagnostic Radiology Department, Mediland Hospital, Baku, Azerbaijan Diagnostic Radiology Department, Avrasiya Hospital, Baku, Azerbaijan Splenosis is a benign condition that could found incidentally and usually asymptomatic. It is associated transplantation of splenic tissue to non-splenic organs after splenic rupture. This process could be triggered after trauma or surgery.The mechanism behind splenic cell autotransplantation begins with the splenic rupture, either from trauma or surgical removal. Seeding of splenic tissue could occur various locations. Subcutaneous splenosis is an extremely rare form of splenosis, mostly observed in abdominal surgical scars. In the presence of coexisting injury to the diaphragm intrathoracic transplantation can occur emerging as single or multiple pleural-based masses. In our case report we describe splenosis combined intrathoracic and subcutaneous involvement, as well as a comprehensive review of the literature. A 64-year-old man, with a past medical history of splenectomy two years ago came to clinic for repairing abdominal hernia. During abdominal CT scan we incidentally found subcutaneous and pleural seeding of splenic tissue. https://pubs.sciepub.com/ajmcr/12/5/4/ajmcr-12-5-4.pdf Splenic trauma Splenosis Subcutaneous nodules Pleural splenosis Diffusion weighted imaging (DWI) Hematoxylin and Eosin (H&E) staining