eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2024-03-17 12 3 42 45 10.12691/ajmcr-12-3-4 AJMCR20241234 article Waad Al Saleemi 1 Amal Al Balushi 1 Ahmed AlAzri 2 Mustafa Al Shaaibi 3 Amina Al-Jardani 4 Azza Al Rashdi 4 Khalsa Al Ramadhani 5 Hala Al Hinai 6 Nawal Al Kindi nawalakindi@gmail.com 6 Medical Microbiology, Oman Medical Speciality Board (OMSB), Oman, Muscat Neurosurgery Department, Khoula Hospital, Oman, Muscat Internal Medicine Department (Infection Disease), Al Nahdha Hospital, Oman, Muscat Central Public Health Laboratories,Ministry Of Health, Oman, Muscat Radiology Department, Khoula Hospital, Oman, Muscat Medical Microbiology Department, Khoula Hospital, Oman, Muscat Brain abscess represents one of the most serious complication of head and neck infections. While anaerobic bacteria are frequent isolates from brain abscesses, usually in a mixed culture, Eikenella corrodens is rarely isolated from this site. E. corrodens is a fastidious gram-negative bacterium that normally colonizes the oral cavity and upper respiratory tract. We report a case of a 42-year-old immunocompetent lady with a background of Ebstein cardiac anomaly who presented with parietooccipital brain abscess. She underwent awake surgery under navigation guidance, burr hole drainage of the abscess. Abscess culture revealed growth of E. corrodens in addition to anaerobic bacterial growth of Fusobacterium nucleatum and Parvimonas micra. The patient was successfully treated with a six weeks course of intravenous ceftriaxone and metronidazole which resulted in complete resolution of the abscess. https://pubs.sciepub.com/ajmcr/12/3/4/ajmcr-12-3-4.pdf brain abscess eikenella corrodens fusobacterium nucleatum parvimonas micra polymicrobial infection oral flora