eng Science and Education Publishing American Journal of Medical Case Reports 2374-216X 2024-03-05 12 3 29 32 10.12691/ajmcr-12-3-1 AJMCR20241231 article Youichi Yanagawa yyanaga@juntendo.ac.jp 1 Hiroki Nagasawa 1 Hiroaki Taniguchi 1 Tatsuro Sakai 1 Ikuto Takeuchi 1 Department of Acute Critical Care Medicine, Shizuoka Hospital, Juntendo University A 79-year-old male presented with decreased blood pressure, weight loss, and episodes of transient loss of consciousness. Diagnosed with neurocardiogenic syncope and vagal nerve paralysis, he experienced a loss of consciousness. Despite initial treatments, syncope persisted. Repeated imaging revealed swelling of neck lymph nodes, diagnosed as carotid sinus syndrome. Lymph node biopsy confirmed malignant lymphoma, prompting thorough dissection. Following diagnosis, syncope episodes ceased. Steroid therapy and radiation were initiated due to weight loss and swallowing difficulties. This case underscores the importance of considering surgical interventions, even when non-invasive treatments fail, in managing carotid sinus syndrome caused by cervical malignant lymphoma. https://pubs.sciepub.com/ajmcr/12/3/1/ajmcr-12-3-1.pdf carotid sinus syndrome malignant lymphoma surgical intervention