eng Science and Education Publishing American Journal of Infectious Diseases and Microbiology 2328-4064 2025-08-04 13 3 44 50 10.12691/ajidm-13-3-1 AJIDM20251331 article Nd¨¦ye Fatou Ngom ndeyetouti98@gmail.com 1 2 3 Awa Ba 3 3 Khardiata Diallo 4 5 Lamyae Nadif 5 Maguette Fall 5 Alassane Ndiaye 5 5 Fulgence Abdou Faye 5 5 Daye Ka 5 5 Oousseynou Ka 5 6 Moussa Seydi 6 6 Department of Medicine, UFRSDD, Alioune Diop University, Bambey Infectious Diseases Department, Fann Hospital, Dakar Introduction: Coronavirus Disease 2019 (COVID-19) is caused by SARS-CoV-2. High rates of venous thromboembolic disease (VTE) are reported in COVID-19, correlating with severe disease and unexplained deaths. This study aimed to characterize VTE development and associated factors in COVID-19 patients hospitalized at SMIT from January to December 2021. Materials and methods: We conducted a retrospective, descriptive, and analytical study of COVID-19 patients with VTE hospitalized at the SMIT, CHNU Fann, Dakar, from January to December 2021. Results: Among 248 hospitalized COVID-19 patients over 12 months, 12 developed VTE, a frequency of 4.84%. Patients were predominantly male (66.67%, sex ratio 1.25) with a mean age of 50.57 years (28-74). Common comorbidities included hypertension, diabetes (both 33.33%), and smoking (25%). RT-PCR was positive in 7 patients, and all 4 patients tested for D-dimer had elevated levels. All patients received corticosteroids and anticoagulation. Antiasthenic were administered in 11 patients, and antibiotics in 10. Only two patients had received a dose of COVID-19 vaccine. The average hospital stay was 10.82 days, with extremes of 1 and 25 days. Smoking was the only significant factor associated with thromboembolic complications. The case fatality rate was 33.33%. Conclusion: Venous thromboembolic complications are common in COVID-19, emphasizing the critical role of COVID-19 prevention. frequent in COVID-19 disease, hence the importance of prevention against COVID-19. https://pubs.sciepub.com/ajidm/13/3/1/ajidm-13-3-1.pdf COVID-19 venous thromboembolic complication SMIT Senegal