eng Science and Education Publishing American Journal of Infectious Diseases and Microbiology 2328-4064 2024-06-17 12 3 44 51 10.12691/ajidm-12-3-1 AJIDM20241231 article Bereket Abraha Molla 1 Dawit Kebede Hulka 2 Amsalu Bekele Binegdie 2 Zekarias Seifu Ayalew 2 Gebeyehu Tessema Azibte gebe10tessema@gmail.com 2 Tseganesh Mokonnen Hailemariam 3 Mahader Nigussie Wosene 3 Meron Y. Berhane 3 Mahlet A. Mechesa 3 Selome Berhanu 3 Genet Hagos Woldemichael 3 Department of Internal Medicine, Addis Ababa University, College of Medicine, Addis Ababa, Ethiopia Division of Pulmonology and Critical Care, Department of Internal Medicine, Addis Ababa University, College of Medicine, Addis Ababa, Ethiopia General Medicine, Department of Internal Medicine, Addis Ababa University, College of Medicine, Addis Ababa, Ethiopia Background: While HIV patients live longer, they can develop non-HIV-related health issues. Chronic obstructive pulmonary disease (COPD) is a concern, but data on COPD in HIV patients in Ethiopia is limited. Objective: This study assessed the prevalence and factors associated with COPD among people living with HIV(PLWH) attending the anti-retroviral therapy (ART) clinic at Tikur Anbesa Specialized Hospital in Addis Ababa, Ethiopia. Methods: Participants underwent screening for COPD using a structured questionnaire that assessed sociodemographic, clinical, and HIV/AIDS-related information. Postbronchodilator spirometry was performed with COPD defined per the Global Initiative for Obstructive Lung Disease (GOLD) criteria (FEV1/FVC) ratio < 0.7. The data was analyzed using SPSS version 26, and factors related to COPD were explored using logistic regression models. Results: Most participants were female (69%) and urban residents (99%). While smoking prevalence was low (9.9%), 66.7% reported exposure to biomass fuel. Chronic respiratory symptoms were common (dyspnea: 39.9%, chronic cough: 22.5%, phlegm: 14.1%, wheezing: 4.2%). COPD prevalence was 4.7% (10/213). Self-reported chronic cough (AOR=4.4, p=0.045) and smoking history (AOR=8.5, p=0.031) were associated with COPD. Conclusion: This study found a high burden of respiratory symptoms but a low prevalence of COPD in PLWH on ART. Chronic cough and smoking were associated with COPD in PLWH. https://pubs.sciepub.com/ajidm/12/3/1/ajidm-12-3-1.pdf HIV COPD spirometry Smoking