Science and Education Publishing American Journal of Cardiovascular Disease Research 4 2 2016 9 1 Superior Mesenteric Artery Thrombosis and Partial Dissection Managed Medically 15 17 EN Muhammad Azharuddin Department of Internal Medicine, Monmouth Medical Center, Long Branch, NJ, USA Ananta Subedi Shil Patel Sweta Chandra AJCDR2016421 10.12691/ajcdr-4-2-1 2016 3 17 2016 6 22 2016 8 30 A 44-year old male presented to the ED complaining of abdominal pain. CT angiography of the abdomen showed thrombus extend from the proximal superior mesenteric artery (3 cm distal to the origin), with partial dissection of the superior mesenteric artery. He was given intravenous fluid and was started on intravenous heparin. All hypercoagulable workup was done to rule out the causes of thrombosis or dissection was negative. The patient's abdominal pain was decreasing, and heparin was bridged with Coumadin. The patient was discharged to home, and advised to check INR regularly and follow up with the vascular surgery department. Conservative management is generally the preferred treatment. For more serious cases, aggressive approaches such as percutaneous endovascular stent placement or surgery would be considered.