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<records>
  <record>
    <language>eng</language>
    <publisher>Science and Education Publishing</publisher>
    <journalTitle>American Journal of Biomedical Research</journalTitle>
    <eissn>2328-3955</eissn>
    <publicationDate>2024-04-11</publicationDate>
    <volume>12</volume>
    <issue>2</issue>
    <startPage>11</startPage>
    <endPage>15</endPage>
    <doi>10.12691/ajbr-12-2-1</doi>
    <publisherRecordId>AJBR20241221</publisherRecordId>
    <documentType>article</documentType>
    <title language="eng">Do Antimicrobial Resistance and Virulence Share Same Genetic Elements</title>
    <authors>
      <author>
        <name>Zangini Nakazwe</name>
        <email>nakazwezangini@gmail.com</email>
        <affiliationId>1</affiliationId>
      </author>
      <author>
        <name>Chipampe Lombe</name>
        <affiliationId>1</affiliationId>
      </author>
    </authors>
    <affiliationsList>
      <affiliationName affiliationId="1">Department of Basic Sciences, University of Lusaka, P.O Box 36711, Lusaka, Zambia</affiliationName>
    </affiliationsList>
    <abstract language="eng">Antimicrobial resistance (AMR) is a growing global health challenge with increased health care costs, mortality and morbidity. Over the years, microbes of clinical importance have coevolved with their hosts and have developed virulence mechanisms through mutations and horizontal gene transfer in order to compete and withstand hash environmental conditions including those posed by antimicrobial agents. Antimicrobial resistance and virulence mechanisms promote survival of microorganisms in their hosts. Several research studies have shown putative association between antimicrobial resistance and virulence but overlooked genetic link between the two. This review focuses on establishing whether antimicrobial resistance and virulence share the same genetic elements.</abstract>
    <fullTextUrl format="pdf">https://pubs.sciepub.com/ajbr/12/2/1/ajbr-12-2-1.pdf</fullTextUrl>
    <keywords language="eng">
      <keyword>Antimicrobial resistance</keyword>
      <keyword>virulence</keyword>
      <keyword>AIEC</keyword>
      <keyword>gene profile</keyword>
    </keywords>
  </record>
</records>