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Nishida Y, Terata N, Ishibashi H, Shibata J, Kodama M. A case report of localized gastric amyloidosis with calcification. Japan J Gastroenterol Surg 1990; 23: 2269-73.

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Article

Pseudotumor Gastric AL Type Amyloidosis Mimicking Malignancy. A Case Report

1Department of Internal Medicine, University Hospital of La Rabta, Rue Jebel Lakhdar, 1002 Tunis, Tunisia


American Journal of Medical Case Reports. 2015, Vol. 3 No. 2, 46-48
DOI: 10.12691/ajmcr-3-2-8
Copyright © 2015 Science and Education Publishing

Cite this paper:
Imed Ben Ghorbel, Nabil BelFeki, Thouraya Ben Salem, Mohamed Habib Houman. Pseudotumor Gastric AL Type Amyloidosis Mimicking Malignancy. A Case Report. American Journal of Medical Case Reports. 2015; 3(2):46-48. doi: 10.12691/ajmcr-3-2-8.

Correspondence to: Imed  Ben Ghorbel, Department of Internal Medicine, University Hospital of La Rabta, Rue Jebel Lakhdar, 1002 Tunis, Tunisia. Email: benghorbelimed@yahoo.com

Abstract

Amyloidosis is an abnormal extracellular deposition of insoluble proteins, which is associated with an involvement of the gastrointestinal tract in 50 to 70% of cases. In primary amyloïdosis (light chain amyloïdosis), localized gastric involvement is a rare finding which can mimick malignancy. We report the case of a 75-year-old woman, admitted with upper digestive outlet obstruction and generalized edema. Upper endoscopy revealed fundic burgeoning ulcerative process. Gastric biopsy concluded to AL type amyloidosis and no malignant tumor was found. Etiological treatment consisted of melphalan and prednisone every 6 weeks. The patient improved from her gastric complaints, and edema. The current decline is 24 months.

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