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Leena Krishnan, John Clark. Non-islet cell tumour hypoglycaemia. BMJ Case Reports (2011).

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Article

Hypoglyceamia due to Paranoeplastic Secretion of Insulin in a Patient with Metastasizing Colon Cancer

1Departement of Endocrinology, Diabetolgy, Hedi Chaker Hospital, Sfax, Tunisia


American Journal of Medical Case Reports. 2015, Vol. 3 No. 2, 34-36
DOI: 10.12691/ajmcr-3-2-4
Copyright © 2015 Science and Education Publishing

Cite this paper:
Nadia Charfi, Lilia Affes, Mouna Elleuch, Wafa Ben Saada, Nabila Rkik, Faten Hadj Kacem, Mouna Mnif, Fatma Mnif, Mohamed Abid. Hypoglyceamia due to Paranoeplastic Secretion of Insulin in a Patient with Metastasizing Colon Cancer. American Journal of Medical Case Reports. 2015; 3(2):34-36. doi: 10.12691/ajmcr-3-2-4.

Correspondence to: Mouna  Elleuch, Departement of Endocrinology, Diabetolgy, Hedi Chaker Hospital, Sfax, Tunisia. Email: elleuch_mouna@yahoo.fr

Abstract

Paraneoplastic hypoglycemia by insulin secreting is rarely described in literature. We review rare cases of paraneoplastic hypoglycemia due to insulin secreting non islet cell tumor diagnosed in a 51 years old patient. This man has an advanced colon cancer with hepatic metastasize. He was admitted in our department for frequent, severe, organic hypoglycemia. Hormonal finding showed elevated serum levels of insulin and c peptide associated with normal serum levels of IGF1 and IGF2. The patient was treated by diet, prednisolone, diazoxid and the metastasize was surgically removed. So that, Hypoglycemia disappeared quickly after the treatment.

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