Derbali F^1,, Ben Fradj F², Rezgui A², Karmani M², Hajji R¹, Ben Abdallah O², Mzabi A², Laouani C²

Agenesis of corpus callosum is the most frequent cerebral malformations. Diagnosis is based on brain imaging. It is most often asymptomatic. Hyperhidrosis can be part of his clinical picture. We present the case of a 49 year old patient, unemployed, with a history of frontal lobe epilepsy and extra pyramidal syndrome. He consulted for a left hemiparesis with sweating attacks. Physical examination showed facial dysmorphism, psychomotor retardation, hemiparesis predominantly left brachiocephalic and bilateral pyramidal syndrome. Brain imaging showed, in addition to cerebral ischemia, a corpus callosum agenesis. This observation helped to highlight a rare disease whose clinical presentation is nonspecific. This malformation is to seek at prenatal, postnatal and even at the adulthood. Hyperhidrosis attacks without obvious underlying pathology should suggest this diagnosis.

corpus callosumage nesis, hyperhidrosis, brain malformations, epilepsy, brainimaging