1Elneelain University
2AlzaemAlazhariUniversity
3Department of Physiology, Faculty of Medicine and Heath Sciences, Alneelain University, Khartoum, Sudan
4Military Hospital
American Journal of Medical Case Reports.
2014,
Vol. 2 No. 12, 266-268
DOI: 10.12691/ajmcr-2-12-2
Copyright © 2014 Science and Education PublishingCite this paper: Amira Humeida, Ihsan M. Osman, Hiba A Awooda, Manal M. ElTahir. Non-secretory Primary Plasma Cell Leukemia – A Case Report.
American Journal of Medical Case Reports. 2014; 2(12):266-268. doi: 10.12691/ajmcr-2-12-2.
Correspondence to: Amira Humeida, Elneelain University. Email:
amirahumeida@yahoo.comAbstract
Plasma cell leukemia (PCL) is a rare disease and the least common variant of multiple myeloma. It accounts for 2-3% of all plasma cell dyscrasias with poor prognosis. We report a 65 year old Sudanese lady presented to oncology clinic with complaint of inability to walk for 2 weeks. Laboratory findings showed anemia, thrombocytopenia and white blood cell count of 49.4x109/L, 62% of which were plasma cells. Bone marrow aspirate showed infiltration by 75% plasma cells some with abnormal forms, Immunophenotyping revealed plasma cell population which were CD38 and CD138 positive, surface, cytoplasmic kappa and lambda were negative. Plasma protein electrophoresis was normal denoting it as non-secretory plasma cell leukemia. Unfortunately the patient passed away before doing further investigations or receiving any treatment.
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