This study aimed to assess blood lipid profile status in pre, post anti-malaria drug treatment in Plasmodium falciparum malaria parasite infected patients and control individuals. Two hundred and two blood samples were collected pre-treatment and post anti-malaria drug treatment. Lipid profile was estimated using CHOD-PAP method; Thick blood film was made. Post treatment HDL was significantly lower compared to pre treatment and control. Pre treatment LDL was significantly higher compared to post treatment and control. Pre treatment triglyceride was significantly higher compared to post treatment and control, pre treatment total cholesterol was significantly lower compared to post treatment and control. Certain lipids are increased while some are decreased with malaria infection/treatment, the rapidly growing malaria parasite requires large amounts of lipids for increase in surface area and volume of its internal membranes, certain serum lipid fractions may favour the onset and/or severity of malaria infection.

malaria parasite, lipid profile and anti-malaria therapy