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Rees TD, Levine RA. Systemic drugs as a risk factor periodontal disease initiation and progression. Compdend contin Educ Dent 1995; 16: 20-42.

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Article

Nonsurgical Management of Amlodipine Induced Gingival Enlargement – A Case Report

1Department of periodontics and oral implantology, Rama dental college hospital & research centre, Kanpur


International Journal of Dental Sciences and Research. 2014, Vol. 2 No. 6, 137-140
DOI: 10.12691/ijdsr-2-6-4
Copyright © 2014 Science and Education Publishing

Cite this paper:
Nitesh kumar Sharma, Roopa D.A.. Nonsurgical Management of Amlodipine Induced Gingival Enlargement – A Case Report. International Journal of Dental Sciences and Research. 2014; 2(6):137-140. doi: 10.12691/ijdsr-2-6-4.

Correspondence to: Nitesh  kumar Sharma, Department of periodontics and oral implantology, Rama dental college hospital & research centre, Kanpur. Email: drniteshsharma@yahoo.com

Abstract

Antihypertensive drugs in the calcium channel blocker group are extensively used in elderly patients. Gingival enlargement associated with Nifedipine was first reported in 1980’s and is very rarely reported to be associated with Amlodipine and Felodipine. The mechanism through which these medications trigger a connective tissue response are still poorly understood. The most effective treatment of drug induced gingival overgrowth is withdrawl or substitution of medication combined with meticulous oral hygiene, plaque control, and removal of local irritants. When these measures fails to resolve the enlargement, surgical intervention is recommended. This case reports a rare case of Amlodipine induced gingival enlargement. The patient was successfully managed by drug substitution and nonsurgical periodontal terapy.

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