Jianwei Zhou^1,, Cui Kong², Zhaocai Zhang¹, Xinke Chen¹, Shuo Shi¹, Liang Han¹

Objective: To analyze the laboratory results of a Sjögren’s syndrome combining autoimmune hepatitis (SS-AIH) with double negative of SSA and SSB (SSA^-SSB^-). Methods: 10 ml venous blood was collected from the patients, and the blood routine, biochemical and immunological indices were respectively detected. Results: The values of WBC, neutrophiles, ESR, ALT, AST, CRP, IgA and IgG were beyond the corresponding reference ranges, respectively. The antinuclear antibody pattern was nuclear homogenous with the titer of 1:1000. The antibodies to PM-Scl, AnuA and Rib-P were all positive. In the fluorescence immune test for AIH, anti-mitochondrial antibodies (AMA) was positive. The concentration of CCP was 92.5 U/ml which also was beyond the reference range. Conclusion: There are certain changes in the laboratory results for the SS-AIH patient with SSA^-SSB^-, and if the changes are the common characters for this kind of disease need further observations in future.

Sjögren’s syndrome, autoimmune hepatitis, SSA, SSB