Lilian Albregard Peripato¹, Monica Taminato², Antonio Francisco Peripato Filho³, Ana Laura Remédio Zeni Beretta^4,

Staphylococcus aureus is a Gram-positive bacterium that colonizes the skin of 30% of healthy individuals. Although considered as a part of the human microbiota, in some conditions, especially in burned patients, Staphylococcus aureus can become pathogenic and cause a wide variety of infections, such as respiratory infections and skin and is responsible for several Infections Related to Health Care (HAI) and community. Therefore, it is necessary to identify the occurrence of methicillin-resistant/sensitive Staphylococcus aureus in burned patients, assessing the mortality related to cases of burn patients infected / colonized. Results: After bibliographic search of the literature presented in the databases 1519 studies were found. In the pre-selection 13 relevant studies were identified, which were discussed with the group of reviewers. Only two met the inclusion criteria of the study. The studies by Kaiser et al (2011) and Reardon et al (1998) were included in this review, addressing the colonization / infection by methicillin-resistant/sensitive Staphylococcus aureus and the mortality for each group. Conclusion: We found that colonization by methicillin-resistant Staphylococcus aureus is associated with burned body surface, so the higher the percentage burned, the greater the risk / colonization by oxacillin- resistant Staphylococcus aureus. Most patients who died were colonized by methicillin-resistant Staphylococcus aureus. The evidence obtained in this study suggests that the burns, especially those infected with methicillin- resistant Staphylococcus aureus, fall into a serious public health problem because of the difficult, and often unsuccessful treatment, which confirms an increase in morbidity and mortality in these patients. We emphasize the importance of this systematic review and meta-analysis of these data to allow the implementation of treatment protocols, improving the quality of preventive measures and reducing mortality rates by methicillin-resistant Staphylococcus aureus.

Resistant Staphylococcus aureus and Methicillin Sensitive, Burn Units, meta-analysis