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Lacy BE, Rosermore J. Helicobacter Pylori: ulcers and more: The beginning of an era. J Nutr. 2001; 131: 2789-93.

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Article

Frequency of Helicobacter Pylori Infection on Histopathology in Patients with Dyspepsia

1Department of Emergency Medicine, Ziauddin University Hospital, North Campus, Karachi


American Journal of Clinical Medicine Research. 2014, Vol. 2 No. 3, 53-56
DOI: 10.12691/ajcmr-2-3-1
Copyright © 2014 Science and Education Publishing

Cite this paper:
Shazia Yasir, Faisal Moin, Syed Mamoon Akhtar. Frequency of Helicobacter Pylori Infection on Histopathology in Patients with Dyspepsia. American Journal of Clinical Medicine Research. 2014; 2(3):53-56. doi: 10.12691/ajcmr-2-3-1.

Correspondence to: Shazia  Yasir, Department of Emergency Medicine, Ziauddin University Hospital, North Campus, Karachi. Email: drshazia24@live.com

Abstract

Objective: To determine the frequency of Helicobacter Pylori infection on histopathology in patients presenting with dyspepsia. Background: Helicobacter Pylori is associated with dyspepsia in patients who have gastric mucosal abnormalities and this infection can be diagnosed by invasive and non invasive test. Histology of endoscopically taken biopsy, for exploration of this organism is used in this study. Study Design: Cross-sectional, observational study. Place and Duration of Study: Department of Emergency Medicine, Ziauddin University Hospital, Karachi for Six months from March 2013 to August 2013. Methodology: A total of 362 cases with dyspeptic symptoms were underwent an upper gastrointestinal endoscopy after fulfilling the selection criteria. H. Pylori infection would be defined by the presence of dyspeptic symptoms with detection of the bacterium on histopathology. All the data was collected by using a proforma and different parameters were assessed for a minimum follow-up period of one month. Data was analyzed by descriptive statistics using SPSS software version 19. Result: Out of 362 cases of dyspepsia 218 (60.2%) males and 144 (39.8%) females (Male: Female was 1.5: 1). Two fifty one (69.3%) patients with dyspepsia were H. Pylori positive on histopathology. Out of 251 cases having H. Pylori infection 165 (75.7%) were male and 86 (59.7%) female. High percentage was found in the age between 31 – 50 years, 160 (77.3%). Conclusion: In this study 69.3% of the patients examined were H. Pylori positive on histopathology. Male sex and older age (> 30 years) are independent risk factor of H. Pylori infection in dyspeptic patients.

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