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Vered M, Wright JM, “Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours”, Head Neck Pathol, 16(1), 63-75, Mar, 2022.

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Article

Maxillary Ameloblastoma, Conventional, Mixed Pattern of Acanthomatous and Basal Cell Subtypes; A Rare Case Report

1Department of Dental Medicine, Kyoto Prefectural University of Medicine Graduate School of Medical Science, 465, Kaji-cho, Hirokoji-Kawaramachi, Kyoto City, Kyoto, Japan

2Department of Diagnostic Pathology, Ogaki Tokushukai Hospital, 6-85 Hayashi-Machi, Ogaki City, Gifu, Japan

3Department of Dental and Oral Surgery, Ogaki Tokushukai Hospital, 6-85 Hayashi-Machi, Ogaki City, Gifu, Japan

4Department of Otolaryngology, Ogaki Toshukai Hospital, 6-85 Hayashi-Machi, Ogaki City Japan


American Journal of Medical Case Reports. 2026, Vol. 14 No. 9, 79-82
DOI: 10.12691/ajmcr-14-9-1
Copyright © 2026 Science and Education Publishing

Cite this paper:
Noriko Matsuzawa, Hideki Mori, Yoshihiro Kimura, Mitsuhiro Aoki. Maxillary Ameloblastoma, Conventional, Mixed Pattern of Acanthomatous and Basal Cell Subtypes; A Rare Case Report. American Journal of Medical Case Reports. 2026; 14(9):79-82. doi: 10.12691/ajmcr-14-9-1.

Correspondence to: Mitsuhiro  Aoki, Department of Otolaryngology, Ogaki Toshukai Hospital, 6-85 Hayashi-Machi, Ogaki City Japan. Email: Mitsuhiro.aoki@tokushukai.jp

Abstract

Ameloblastoma (AM) is a benign but locally infiltrative epithelial odontogenic neoplasm. An 86-year-old woman presented with swelling on the left palate gum. CT images as well as panoramic X-ray photograph displayed a multiocular radiolucent lesion extending from the alveolar process to the plate. Pathological diagnosis of the resected tumor tissue was AM arisen from the anterior maxillary bone. AM can present with a follicular, plexiform, acanthomatous, basal cell, granular or desmoplastic subtype. Present case was diagnosed as a mixed pattern of acanthomatous subtype and basal cell subtype. In this study, tumor cells of the basal cell type had a clear continuity to the islands of acanthomatous subtype suggesting that the cells of basal type could differentiate to those of acanthomatous islands. To the best of our knowledge, presence of the unique combination of acanthomatous subtype and basal cell subtype, and the mutual correlation with two subtypes of AM have not yet been described.

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