1Félix Houphouët-Boigny University, Faculty of Biosciences, Laboratory of Biotechnology, Agriculture and Valorization of Biological Resources, Côte d’Ivoire, 22 BP 582 Abidjan 22
2Antibiotics, Natural Substances and Antimicrobial Resistance Surveillance Unit of the Pasteur Institute of Côte d’Ivoire, Abidjan, Côte d’Ivoire, 01 BP 490 Abidjan 01
American Journal of Microbiological Research.
2026,
Vol. 14 No. 1, 1-6
DOI: 10.12691/ajmr-14-1-1
Copyright © 2026 Science and Education PublishingCite this paper: Eric Joël TAHOU, Kouadio Fernique KONAN, Bertin Konan TIEKOURA, Assanvo Simon-Pierre N’GUETTA, Kouadio Nathalie GUESSENND. Antibiotic Resistance and Detection of Qnr Genes in isolated Uropathogenic Bacteria from Patients with Urinary Catheters.
American Journal of Microbiological Research. 2026; 14(1):1-6. doi: 10.12691/ajmr-14-1-1.
Correspondence to: Eric Joël TAHOU, Félix Houphouët-Boigny University, Faculty of Biosciences, Laboratory of Biotechnology, Agriculture and Valorization of Biological Resources, Côte d’Ivoire, 22 BP 582 Abidjan 22. Email:
tahoujojo@gmail.comAbstract
Antibiotic resistance in bacteria is a serious global public health problem. This study aimed to characterize antibiotic resistance genes in patients with urinary catheters. The study involved bacterial strain collection, antibiotic susceptibility testing, and molecular characterization for the detection of genes mediated by fluoroquinolone resistance. A total of 81 strains were collected. Strain distribution showed that Staphylococcus aureus was the most prevalent species (44.44%, n=36). Resistance profiling showed that coagulase-negative Staphylococcus strains (n=12) and Acinetobacter baumannii strains (n=5) expressed 100% resistance to cefoxitin and all tested beta-lactam antibiotics, respectively. Acinetobacter baumannii was resistant to ciprofloxacin (100%, n=5). However, amikacin showed greater activity against Pseudomonas aeruginosa (n=28) and Acinetobacter baumannii (n=5) strains, with 25% and 0% activity, respectively. Molecular gene characterization identified the qnr A, qnr B, and qnr S genes. The strains exhibited a high diversity of resistance genes, with 12.5%, 77.5%, and 60% observed in qnr A, qnr B, and qnr S, respectively. Co-expression of fluoroquinolone resistance genes was demonstrated in 30 strains. This study highlights the high prevalence of antibiotic-resistant bacteria and underscores the crucial role of microbiological and molecular surveillance of bacteria. The results highlight the need for rigorous antibiotic management to prevent the spread of resistant strains.
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