1Department of Biochemistry-Genetics, Training and Research Unit Biological Sciences, Peleforo Gon Coulibaly University, Korhogo, Côte d’Ivoire
2Department of Microbiology and Molecular Biology, Training and Research Unit of Agriculture, Fisheries Resources and Agro-Industry, University of San Pedro, San Pedro, Côte d’Ivoire
3Department of Biology and Health, Training and Research Unit of Bioscience, Felix Houphouet-Boigny University, Abidjan, Côte d’Ivoire
American Journal of Microbiological Research.
2025,
Vol. 13 No. 2, 28-32
DOI: 10.12691/ajmr-13-2-2
Copyright © 2025 Science and Education PublishingCite this paper: KONE Monon, TOURE Daouda, KOKORA Aya Philomene, KOFFI Kouadio Guy Roland, TOURE Abdoulaye, OUATTARA Karamoko, COULIBALY Adama. Evaluation of the Antibacterial Activity of Extracts of Alchornea Cordifolia (Schum Et Thonn Mull) Leaves on the in Vitro Growth of Ureolytic Germs Isolated from Urethral Samples At the Korhogo Rural Hospital Centre, North Côte d’Ivoire.
American Journal of Microbiological Research. 2025; 13(2):28-32. doi: 10.12691/ajmr-13-2-2.
Correspondence to: KONE Monon, Department of Biochemistry-Genetics, Training and Research Unit Biological Sciences, Peleforo Gon Coulibaly University, Korhogo, Côte d’Ivoire. Email:
konemonon2017@gmail.comAbstract
The germs involved in urinary tract infections are a major concern for clinicians. The increasing multi-resistance of these bacteria to conventional antibiotics is a real public health problem. The aim of this study was to contribute to the treatment of urinary tract infections using the leaves of Alchornea cordifolia. The leaves were subjected to two extraction methods (infusion and hydro-ethanolic maceration). A tri-phytochemical analysis using colorimetry and tube precipitation revealed the polyphenol composition of the extractsThe sensitivity of the extracts was assessed by agar well diffusion and the antibacterial parameters determined by diffusion in liquid medium followed by spreading on Mueller Hinton agar. The results showed that the extracts were rich in sterols, polyterpenes, polyphenols, flavonoids, tannins, alkaloids and saponins, and possessed interesting antibacterial activity. All strains were sensitive to extremely sensitive to A. cordifolia extracts at 50 mg/ mL. Low MIC values ranging from 0.78 to 12.5 mg/mL were recorded. All the extracts had a bactericidal effect on all the strains tested. This plant has good antibacterial activity and is therefore a good candidate for the treatment of urinary tract infections.
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