Hesham Mohamed Abdal-Salam Yehia^1,, Said Mahmoud Said²

Herpes simplex virus type 1 (HSV-1) is a member of the Herpesviridae family and is a common human pathogen. Herpes simplex virus type 1 (HSV-1) infection is a highly prevalent viral infection that affects a large portion of the population worldwide. The development of effective antiviral agents to combat HSV-1 is of great importance. In this study, we aimed to evaluate the efficacy of two potential antiviral candidates, OCTA-H and Octa-Gel, against HSV-1 infection. The assay was conducted using a BSC-III cabinet level 3 III under Germfree conditions to ensure accurate assessment of antiviral activity. The results demonstrated that both OCTA-H and Octa-Gel exhibited significant antiviral activity against HSV-1, with OCTA-H demonstrating a higher level of efficacy compared to Octa-Gel. These findings highlight the potential of OCTA-H as a promising candidate for further development as an antiviral agent against HSV-1.

OCTA-H, Octa-Gel, HSV-1, antiviral activity, efficacy