1University of Florida, Department of Internal Medicine1, Gainesville, FL
American Journal of Medical Case Reports.
2023,
Vol. 11 No. 11, 167-168
DOI: 10.12691/ajmcr-11-11-1
Copyright © 2023 Science and Education PublishingCite this paper: Adrian M. Alonso, Matilda L. Culp. Clinical Presentation and Successful Treatment of a Patient with Anti-SUMO-activating Enzyme Subunit 1 (SAE1) Dermatomyositis.
American Journal of Medical Case Reports. 2023; 11(11):167-168. doi: 10.12691/ajmcr-11-11-1.
Correspondence to: Adrian M. Alonso, University of Florida, Department of Internal Medicine1, Gainesville, FL. Email:
Adrian.alonso@medicine.ufl.eduAbstract
Anti-SAE1 antibody is a rarely reported, myositis-specific antibody, which is most clinically associated with affecting the gastrointestinal tract, skin, and lungs. This case demonstrates a patient presenting to the hospital with signs of dermatomyositis, later found to be anti-SAE1 positive. He was promptly treated with immunosuppressive medications, including IVIG, a novel therapeutic agent for dermatomyositis. This case further elucidates the importance of identifying anti-SAE1-positive patients in dermatomyositis.
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