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Michael J.W., Beth A. Ahner, Determination of stability constants of Cu(I), Cd(II) & Zn(II) complexes with thiols using fluorescent probes, Journal of Inorganic Biochemistry, Volume 128, November 2013, Pages 112-123.

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Article

Stability Constant Determination of Substituted Thiopyrimidine Glucosides with Ni(II), Cu(II) and Zn(II)

1Department of Chemistry, Institute of Science College, Nagpur (MS) India

2Jawaharlal Nehru Arts, Commerce and Science College, Wadi, Nagpur (MS) India

3Department of Chemistry, Institute of Forensic Science College, Nagpur (MS) India

4R. S. Bidkar College, Hanganghat, Wardha, (MS), India


World Journal of Analytical Chemistry. 2023, Vol. 8 No. 1, 1-5
DOI: 10.12691/wjac-8-1-1
Copyright © 2023 Science and Education Publishing

Cite this paper:
R. R. Tayade, R. K. Wanare, A. A. Sukhadeve, R. G. Mahakale. Stability Constant Determination of Substituted Thiopyrimidine Glucosides with Ni(II), Cu(II) and Zn(II). World Journal of Analytical Chemistry. 2023; 8(1):1-5. doi: 10.12691/wjac-8-1-1.

Correspondence to: R.  R. Tayade, Department of Chemistry, Institute of Science College, Nagpur (MS) India. Email: rrtchem@gmail.com, rajwanare@rediffmail.com

Abstract

Substituted thiopyrimidine glucosides are of great biological importance, but their metal-binding properties with biologically-relevant are not well investigated. Stability constants of the substituted thiopyrimidine glucosides with Ni(II), Cu(II) and Zn(II) metal were determined by . Substituted Thiopyrimidine Glucosides drugs are synthesized by reported method. The physic-chemical study of substituted thiopyrimidine carried out by pH-metric method by considering their interaction with Ni(II), Cu(II) and Zn(II) metal ions at 0.1 M ionic strength in 70 % DMF-water mixture by Bjerrum method as adopted by Calvin and Wilson. This study is useful to understand type of complex formation between transition metal ion and thiopyrimine glucosides drugs (L1 and L2). Present work deals with determination and comparison of stability constant.

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