1Department of Chemistry, Institute of Science College, Nagpur (MS) India
2Jawaharlal Nehru Arts, Commerce and Science College, Wadi, Nagpur (MS) India
3Department of Chemistry, Institute of Forensic Science College, Nagpur (MS) India
4R. S. Bidkar College, Hanganghat, Wardha, (MS), India
World Journal of Analytical Chemistry.
2023,
Vol. 8 No. 1, 1-5
DOI: 10.12691/wjac-8-1-1
Copyright © 2023 Science and Education PublishingCite this paper: R. R. Tayade, R. K. Wanare, A. A. Sukhadeve, R. G. Mahakale. Stability Constant Determination of Substituted Thiopyrimidine Glucosides with Ni(II), Cu(II) and Zn(II).
World Journal of Analytical Chemistry. 2023; 8(1):1-5. doi: 10.12691/wjac-8-1-1.
Correspondence to: R. R. Tayade, Department of Chemistry, Institute of Science College, Nagpur (MS) India. Email:
rrtchem@gmail.com, rajwanare@rediffmail.comAbstract
Substituted thiopyrimidine glucosides are of great biological importance, but their metal-binding properties with biologically-relevant are not well investigated. Stability constants of the substituted thiopyrimidine glucosides with Ni(II), Cu(II) and Zn(II) metal were determined by . Substituted Thiopyrimidine Glucosides drugs are synthesized by reported method. The physic-chemical study of substituted thiopyrimidine carried out by pH-metric method by considering their interaction with Ni(II), Cu(II) and Zn(II) metal ions at 0.1 M ionic strength in 70 % DMF-water mixture by Bjerrum method as adopted by Calvin and Wilson. This study is useful to understand type of complex formation between transition metal ion and thiopyrimine glucosides drugs (L1 and L2). Present work deals with determination and comparison of stability constant.
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