Ghonem Elsayed Ghonem^1,, Yosreah Mohamed Mohamed², Samia Hussieny Gaballah¹, Manal Salah Hassan²

Background: improving nurses’ practice regarding thrombolytic therapy will prevent the complications resulting from error of administration of thrombolytics, which will have a direct impact on patient's progress and decrease hospital stay. Aim of the study: Evaluate the effect of educational program on nurses' knowledge and practice regarding thrombolytic therapy among patients with acute myocardial infarction, Design: Quasi-experimental research design was used in the study. Setting: The present study was carried out at Critical Care Units affiliated to the Suez Canal University Hospital, Subject: A convenient sample of all available staff nurses (40 nurses) who were working at the previously mentioned settings, Tools of data collection: The data were collected using two tools named nurses' knowledge assessment questionnaire and nurses' observational checklist. Results: The majority of studied nurses (92.5%) had satisfactory level of knowledge regarding thrombolytic therapy post intervention of educational program. The post and follow up-intervention mean knowledge score was high 23.425, 21.825 respectively when compared with pre-intervention mean practice score 13.45 with P value < .001. also, the majority of studied nurses (97.5%) had satisfactory level of practice regarding thrombolytic therapy post intervention of educational program. The post and follow up-intervention mean practice score was high 37.95, 36.05 respectively when compared with pre-intervention mean practice score 24.05 with P value < .001. Conclusion: there was statistically significant improvement in the nurses' knowledge and practice mean scores regarding thrombolytic therapy in post and follow up phases compared to pre- program implementation phase. Recommendation, regular Application of educational programs to improve nurse's practice in competent level related to administration of thrombolytic therapy.

myocardial infarction, thrombolytic therapy, educational program, nurses' knowledge and practice