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Olgac U, Knight J, Poulikakos D. Computed high concentrations of low-density lipoprotein correlate with plaque locations in human coronary arteries. Journal of Biomechanics 2011; 44 (13): 2466-2471.

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Article

Body Fats Accumulate Metabolic Products: Physical and Chemical Analysis in Vitro

1Republican Scientific Center for Emergency Medicine, Astana, the Republic of Kazakhstan

2Astana Medical University, Astana, the Republic of Kazakhstan

3Karaganda State Medical University, Karaganda, the Republic of Kazakhstan


American Journal of Medical and Biological Research. 2014, Vol. 2 No. 1, 5-11
DOI: 10.12691/ajmbr-2-1-2
Copyright © 2014 Science and Education Publishing

Cite this paper:
Kuat Pernekulovich Oshakbayev, Kenneth Alibek, IgorOlegovich Ponomarev, Nurlybek Nurlanovich Uderbayev, Bibazhar Abayevna Dukenbayeva, Meruyert Gazaliyeva, Pernekul Oshakbayev, Sholpan Kaliyeva. Body Fats Accumulate Metabolic Products: Physical and Chemical Analysis in Vitro. American Journal of Medical and Biological Research. 2014; 2(1):5-11. doi: 10.12691/ajmbr-2-1-2.

Correspondence to: Kuat  Pernekulovich Oshakbayev, Republican Scientific Center for Emergency Medicine, Astana, the Republic of Kazakhstan. Email: okp.kuat@mail.ru

Abstract

Objective: Aim of our study is to investigate physical and chemical structure and properties of body lipids at various anatomical sites. Trial design: A pilot physical and chemical descriptive experimental trial in vitro. Methods and Participants: Adipose tissue in the amount of 252 samples from 36 individuals (17 dead females) at autopsy. The subjects had died from various injuries and were between 36-60 years old. Interventions: Chemical groups and compounds were studied on infrared spectrometry with software, and atomic adsorptive analysis on spectrometer. Elemental chemical analysis of lipids different localization carried out. Research Subject: Chemical elements and compounds. Results: The highest levels of saturated fatty acids and almost all chemical groups and compounds analysed are found in dense atherosclerotic plaque (AP). In those samples, relatively more compounds containing metabolic products were identified (P < 0.05, n = 252). Dense AP contains relatively more saturated and branched hydrocarbon chains, and they have the largest quantities of organic and inorganic elements and compounds in their structure. Conclusions: Human body lipids, especially dense AP, serve as a depot for various organic substances. Once having been formed, the AP has its own pathophysiological role in adsorption of redundant waste products.

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