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Kessenbrock K., Krumbholz M., Schönermarck U., et al.: Netting neutrophils in autoimmune small-vessel vasculitis. Nature Medicine. 2009; 15 (6): 623-625.

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Article

Pauci-immune Crescentic Glomerulonephritis: Case Report

1Department of Internal Medicine, Beaumont Hospital, Dearborn, MI

2Wayne State University, School of Medicine, Detroit, MI

3Pathology Department, Oakland University William Beaumont School of Medicine

4Division of Nephrology, Internal Medicine Department, Beaumont Hospital, Dearborn, MI


American Journal of Medical Case Reports. 2022, Vol. 10 No. 3, 45-47
DOI: 10.12691/ajmcr-10-3-1
Copyright © 2022 Science and Education Publishing

Cite this paper:
Wisam Mnkana, Nikita Wong, Eman EL-Sawalhy, Ahmed Abdelrahim, Hussein Gaith, Zhang Ping, Rabih Bazzi. Pauci-immune Crescentic Glomerulonephritis: Case Report. American Journal of Medical Case Reports. 2022; 10(3):45-47. doi: 10.12691/ajmcr-10-3-1.

Correspondence to: Eman  EL-Sawalhy, Department of Internal Medicine, Beaumont Hospital, Dearborn, MI. Email: Eman.elsawalhy@beaumont.org

Abstract

Pauci-immune glomerulonephritis ( PIGN) is a potentially life-threatening condition that progresses rapidly to renal failure within days or weeks. Here we present a 62 -year-old African American female who was found to have acute kidney injury at the time of presentation. Further workup including renal biopsy showed anti-neutrophilic cytoplasmic antibodies (ANCA) associated pauci-immune crescentic glomerulonephritis. The patient was started on steroids and cyclophosphamide however, the patient’s kidney function continued to get worse and required hemodialysis. Unfortunately, our patient passed away after two months of diagnosis secondary to cardiac arrest.

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