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Article

Thrombotic Microangiopathy in Autopsy-Confirmed Lung Signet Ring Cell Carcinoma

1Departamento de Medicina Interna, Hospital Universitario “José E. González”, Monterrey, México

2Departamento de Patología, Hospital Universitario “José E. González”, Monterrey, México

3Departamento de Hematología, Hospital Universitario “José E. González”, Monterrey, México


American Journal of Medical Case Reports. 2022, Vol. 10 No. 2, 22-25
DOI: 10.12691/ajmcr-10-2-1
Copyright © 2022 Science and Education Publishing

Cite this paper:
Carlos E. Gonzalez, Luis A. Gonzalez, Luis A. Cesenas, Olga G. Cantu. Thrombotic Microangiopathy in Autopsy-Confirmed Lung Signet Ring Cell Carcinoma. American Journal of Medical Case Reports. 2022; 10(2):22-25. doi: 10.12691/ajmcr-10-2-1.

Correspondence to: Carlos  E. Gonzalez, Departamento de Medicina Interna, Hospital Universitario “José E. González”, Monterrey, México. Email: carloseugenio_00@hotmail.com

Abstract

Thrombotic Microangiopathy (TMA) has been described as a rare paraneoplastic syndrome. We present a patient with Coombs-negative hemolytic anemia and schistocytes in a peripheral blood smear, fulfilling diagnosis criteria for TMA. After patients death, an autopsy report revealed bone infiltrating signet ring cell carcinoma, identifying the lung as the primary tumor origin.

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