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Zhao Y, He J, Wang J, et al. Development of pancytopenia in a patient with COVID-19. J Med Virol. Mar 2021; 93(3): 1219-1220.

has been cited by the following article:

Article

New Onset Aplastic Anemia after a COVID-19 Infection: A Case Report

1Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, United States


American Journal of Medical Case Reports. 2021, Vol. 9 No. 9, 451-455
DOI: 10.12691/ajmcr-9-9-4
Copyright © 2021 Science and Education Publishing

Cite this paper:
Vikram Sumbly, Raheel Siddiqui, Mohsen Alshamam, Tamara Kurbanova, Vincent Rizzo. New Onset Aplastic Anemia after a COVID-19 Infection: A Case Report. American Journal of Medical Case Reports. 2021; 9(9):451-455. doi: 10.12691/ajmcr-9-9-4.

Correspondence to: Vikram  Sumbly, Internal Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, Jamaica, United States. Email: vikram.sumbly@gmail.com

Abstract

Aplastic anemia (AA) is a potentially life-threatening acquired bone marrow failure syndrome which leads to central pancytopenia. Although the exact pathogenesis of this disorder is yet to be fully understood, it is thought to be primarily caused by auto-immunity. Unlike other viruses, the association between SARS CoV-2 and AA remains insufficiently explored in current literature. Based on the few cases of COVID-19-induced central pancytopenia and the available literature on virus-induced AA, we propose that the development of AA in COVID-19 patients may be attributable to SARS CoV-2. We report the case of a 29-year-old female that developed AA after being hospitalized for COVID-19. She had a favorable clinical outcome after several courses of immunosuppressive therapy.

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