Article citationsMore >>

J. Dalmau et al., “Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies,” Lancet Neurol., vol. 7, no. 12, pp. 1091-1098, Dec. 2008.

has been cited by the following article:

Article

A Rare Case of Anti-NMDA Receptor Encephalitis Associated with an Ovarian Teratoma

1Alfaisal University College of Medicine, Riyadh, Saudi Arabia 11533

2Department of Internal Medicine, Spectrum Health Butterworth Hospital, Grand Rapids, Michigan, USA 49503

3Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA


American Journal of Medical Case Reports. 2021, Vol. 9 No. 7, 354-357
DOI: 10.12691/ajmcr-9-7-3
Copyright © 2021 Science and Education Publishing

Cite this paper:
Eiad Habib, Jay Patel, Connor Kerndt, Dan Summers, TaLawnda Bragg. A Rare Case of Anti-NMDA Receptor Encephalitis Associated with an Ovarian Teratoma. American Journal of Medical Case Reports. 2021; 9(7):354-357. doi: 10.12691/ajmcr-9-7-3.

Correspondence to: Eiad  Habib, Alfaisal University College of Medicine, Riyadh, Saudi Arabia 11533. Email: eiadhabib8@gmail.com

Abstract

Anti-N-methyl-D-aspartate (NMDA)-receptor encephalitis is a syndrome of psychiatric symptoms and neurologic sequelae that is commonly associated with an ovarian teratoma. The antagonism of cerebral NMDA receptors disrupts normal brain activity causing acute onset psychological disturbances including mania, psychosis, or anxiety. Due to the rarity of the condition, diagnosis may be delayed as other common disorders such as primary psychiatric disorders or infectious encephalitis are ruled out. With rapid diagnosis and management, including resection of the tumor and immunotherapy, positive outcomes may be achieved. We present the case of a 25-year-old female with neuropsychiatric manifestations and an ovarian teratoma who was subsequently diagnosed with anti-NMDA-receptor encephalitis.

Keywords