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Konety SH, Olshansky B . The "pill-in-the-pocket" approach to atrial fibrillation. N Engl J Med 2005; 352: 1150-1.

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Article

A Classical Wide Complex Tachycardia due to Propafenone Toxicity; Uncommon Side Effect of a Commonly Used Medication

1Department of Internal Medicine, Beaumont Hospital-Dearborn, Michigan, USA

2Division of Nephrology, Department of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, Michigan, USA

3Division of Cardiovascular Medicine, Department of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, Michigan, USA


American Journal of Medical Case Reports. 2021, Vol. 9 No. 4, 229-231
DOI: 10.12691/ajmcr-9-4-6
Copyright © 2021 Science and Education Publishing

Cite this paper:
Hammam Shereef, Mohamedanwar Ghandour, Sarah Abdelsamad, Ahmed Subahi, Ahmed S Yassin, Luis Afonso. A Classical Wide Complex Tachycardia due to Propafenone Toxicity; Uncommon Side Effect of a Commonly Used Medication. American Journal of Medical Case Reports. 2021; 9(4):229-231. doi: 10.12691/ajmcr-9-4-6.

Correspondence to: Mohamedanwar  Ghandour, Division of Nephrology, Department of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, Michigan, USA. Email: mr.anwar90@yahoo.com

Abstract

Propafenone is a Class 1 C anti-arrhythmic drug, frequently used in the treatment of supraventricular and ventricular arrhythmias. We herein are presenting a case of 67-year-old female who presented with wide complex tachycardia consistent with Propafenone toxicity and who responded immediately to sodium bicarbonate injections. This case shines the light on a common effect of Propafenone toxicity and aims to increase the clinician awareness about such a documented reaction, that can be reversed by a simple treatment like sodium bicarbonate.

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