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Pierro A, Koletzko B, Carnielli V, Superina RA, Roberts EA, Filler RM, et al. Resting energy expenditure is increased in infants and children with extrahepatic biliary atresia. J Pediatr Surg. 1989; 24: 534-8.

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Article

In a Time of Pandemic: Predictors for Post-transplant Respiratory Complications

1Consultant Hepatobiliary and Liver Transplant Surgeon, India


International Journal of Celiac Disease. 2021, Vol. 9 No. 1, 12-15
DOI: 10.12691/ijcd-9-1-4
Copyright © 2021 Science and Education Publishing

Cite this paper:
Bhavin Vasavada. In a Time of Pandemic: Predictors for Post-transplant Respiratory Complications. International Journal of Celiac Disease. 2021; 9(1):12-15. doi: 10.12691/ijcd-9-1-4.

Correspondence to: Bhavin  Vasavada, Consultant Hepatobiliary and Liver Transplant Surgeon, India. Email: drbhavin.liversurgeon@gmail.com

Abstract

Introduction: Biliary atresia is commonly associated with malnutrition and failure to thrive. Very few studies have been published on the impact of preoperative malnutrition on post-transplant outcomes in these children. Material and Methods: 110 children underwent living donor liver transplantation from January 2003 to March 2013. Pre-transplant malnutrition was defined according to z scores for the weight for age and height for age as per who definition. Patients having both Z score of < -2 were compared with the control group. Statistical analysis was done using SPSS version 21 (IBM). Results: 39 children out of 110 were having z score for the weight for age < -2. There was no statistical difference between PELD score, graft weight, GRWR, intraoperative blood loss between to groups. 22 out of 39 patients in malnourished group developed clavein grade 3, grade 4 complications and 32 patients out of 71 in the control group developed clavien grade 3 grade 4 complications. (p= 0.318). The overall mortality rate was 4.5% and mortality rates in the malnourished vs control group were respectively 7.69% and 2.81% (p= 0.278). A total of 14 patients developed postoperative pulmonary complications. Pulmonary complications were significantly high in the malnourished group. p=0.003. Conclusion: Preoperative malnutrition is associated with a high postoperative pulmonary complication rate in liver transplantation for biliary atresia.

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