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Bechthold A, Boeing H, Schwedhelm C, Hoffmann G, Knüppel S, Iqbal K, et al. Food groups and risk of coronary heart disease, stroke and heart failure: A systematic review and dose-response meta-analysis of prospective studies. Crit Rev Food Sci Nutr. 2019; 59: 1071-1090.

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Article

The Gut Feeling of the Heart: Pathophysiological Pathways in the Gut-heart Axis in Celiac Disease

1Chaim Sheba Medical Center, The Zabludowicz Research Center for Autoimmune Diseases, Tel Hashomer, Israel

2Institute for Health Sciences from Federal University of Bahia, Salvador, Bahia, Brazil


International Journal of Celiac Disease. 2020, Vol. 8 No. 4, 120-123
DOI: 10.12691/ijcd-8-4-2
Copyright © 2020 Science and Education Publishing

Cite this paper:
Aaron Lerner, Jozélio Freire de Carvalho. The Gut Feeling of the Heart: Pathophysiological Pathways in the Gut-heart Axis in Celiac Disease. International Journal of Celiac Disease. 2020; 8(4):120-123. doi: 10.12691/ijcd-8-4-2.

Correspondence to: Aaron  Lerner, Chaim Sheba Medical Center, The Zabludowicz Research Center for Autoimmune Diseases, Tel Hashomer, Israel. Email: aaronlerner1948@gmail.com

Abstract

The chain of events, starting from nutrients that change microbiome/dysbiome ratio followed by their secreted mobilome and ending with the leaky gut syndrome, can be applied for cardiovascular diseases. The Gut-heart axis is only one avenue where intestinal luminal eco-events induce remote organ's pathology. The present editorial highlights the mechanisms and potential pathways in the nutrients-microbiota-endocrine-cardiovascular axis that might affect human heart morbidity and mortality in celiac disease.

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