Article citationsMore >>

Latisha D. Heinlen Lauren L. Ritterhouse Micah T. McClain Ribosomal P Auto antibodies are Present before SLE Onset and are directed against non-C Terminal Peptides. J Mol Med (Burl). 2010 July; 88(7): 719-727.

has been cited by the following article:

Article

Ribosomal P Antibodies Preceding the Onset of Sle-A Case Report


American Journal of Clinical Medicine Research. 2013, Vol. 1 No. 2, 26-27
DOI: 10.12691/ajcmr-1-2-1
Copyright © 2013 Science and Education Publishing

Cite this paper:
Prashanth N C, Satyanarayana. N, T. AnilKumar, Ravikumar. R. Ribosomal P Antibodies Preceding the Onset of Sle-A Case Report. American Journal of Clinical Medicine Research. 2013; 1(2):26-27. doi: 10.12691/ajcmr-1-2-1.

Correspondence to: T. AnilKumar, . Email:

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by the Production of auto antibodies directed against a variety of nuclear and cytoplasmic antigens. Auto antibodies to ribosomal Proteins are found in 15–30% of systemic lupus erythematosus (SLE) patients. Ribosomal P antibody is shown to predict SLE 1.7 years before clinical onset of SLE. This is a case of 28 year old female patient with a malar rash and nonspecific neurologic symptoms .The antibody profile showed that ANA ,anti- Ds dna and anti- Sm antibodies were negative but anti ribosomal P0 antibody was strongly positive(+++) at presentation. A strong clinical suspicion and careful follow-up helped in making a diagnosis of SLE over a period of nine months.

Keywords