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Article

The Impact of Secondary Metabolites Produced by Streptomyces on Uro-pathogens

1Department of Botany, Faculty of Science, University of Khartoum


American Journal of Microbiological Research. 2020, Vol. 8 No. 3, 103-109
DOI: 10.12691/ajmr-8-3-4
Copyright © 2020 Science and Education Publishing

Cite this paper:
Suhndh Ahmed Mohmmed Musa. The Impact of Secondary Metabolites Produced by Streptomyces on Uro-pathogens. American Journal of Microbiological Research. 2020; 8(3):103-109. doi: 10.12691/ajmr-8-3-4.

Correspondence to: Suhndh  Ahmed Mohmmed Musa, Department of Botany, Faculty of Science, University of Khartoum. Email: suhndh87@gmail.com

Abstract

Soil streptomyces are known as a rich source to produce secondary metabolites. This study was conducted to examine the effect of the Streptomyces sp. extracts against the uro-pathogen isolates from urinary tract infections in pregnancy from Kassala state. Cultural, morphological and physiological characterization of 15 microorganisms isolates from four soil samples indicated that all isolates belonged to the Streptomyces genus. All Streptomyces isolates produced chitinase enzyme except isolate SU11. After 72 hours all of the isolates were produced L-asparaginase enzyme. Ethyl acetate extracts of Antimicrobial were used for secondary screening against uro-pathogen. The high activity has been observed against Gram-positive bacteria with a percentage of 73.3% when compared to gram-negative bacteria. Whilst 26.7% has a high activity against Gram-negative comparing with Gram-positive bacteria, and different activity was shown against candida spp.

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