Calcifying epithelial odontogenic tumor (CEOT) is a benign epithelial odontogenic tumor which is characterized by the presence of islands and sheets of epithelial cells, amyloid like material and calcifications. These calcifications have a concentric lamellar pattern known as “Liesegang Rings” (LRs). So far It is highlighted that LRs developed mostly in intraosseous lesions having amyloid like materials which later transformed to calcification. Many variants of histopathology discussed in this article to emphasize importance of calcification in CEOT. Although LRs are considered to be pathognomic to CEOT when it comes to odontogenic lesions, this term has sometimes been used for adenomatoid odontogenic tumor (AOT) where concentric lamellar calcifications have also been reported. However, here question arises, are LiesegangRings the misnomer in calcifying epithelial odontogenic tumor? Yes, at some aspects on basis of the different etiology, the appearance, and staining patterns. To conclude in view of literatures that phenomena of “Liesegang ring pattern of calcification” is to be more appropriate found in odontogenic tumors.

CEOT, Liesegang Rings (LRs), calcification