1Department of Medicine, State University of New York Downstate Medical Center, Brooklyn, USA
2Department of Pathology, State University of New York Downstate Medical Center, Brooklyn, USA
3Therapath Neuropathology, New York, USA
4Department of Rheumatology, New York University Langone Hospital, Brooklyn, USA
American Journal of Medical Case Reports.
2020,
Vol. 8 No. 9, 306-310
DOI: 10.12691/ajmcr-8-9-12
Copyright © 2020 Science and Education PublishingCite this paper: Michael Trevisonno, Daniel E. Diaz, Steven S. Chin, FCAP Jenny Libien, Yamen Homsi. Anti-EJ Antisynthetase Syndrome Associated with Mycobacterium Tuberculosis Infection.
American Journal of Medical Case Reports. 2020; 8(9):306-310. doi: 10.12691/ajmcr-8-9-12.
Correspondence to: Michael Trevisonno, Department of Medicine, State University of New York Downstate Medical Center, Brooklyn, USA. Email:
michael.trevisonno@downstate.eduAbstract
Antisynthetase Syndrome is a rare type of idiopathic inflammatory myopathy. It is characterized by interstitial lung disease, non-erosive arthritis, Raynaud’s phenomenon, and mechanic’s hands. Diagnosis is confirmed with the detection of an antibody directed against amino-acyl transferase RNA. Opportunistic infections are common causes of mortality in patients with autoimmune diseases. Immunosuppressive treatment further contributes to the risk of infection. We report, for the first time in the literature, a 62-year-old woman diagnosed with Anti-EJ antisynthestase syndrome who died from disseminated mycobacterial tuberculosis infection. This case emphasizes the importance of early recognition and prompt treatment of opportunistic infections in order to decrease mortality.
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