Article citationsMore >>

Hoffmann M, Kleine-Weber H, Schroeder S, et al. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor. Cell. 2020; 181(2): 271-280. e278.

has been cited by the following article:

Article

Management of ST-Elevation Myocardial Infarction in the COVID-19 Era: The Role of Thrombosis and Anticoagulation Strategy

1Department of Medicine, SUNY Downstate health Sciences University, Brooklyn, NY

2Division of Cardiovascular Medicine, SUNY Downstate health Sciences University, Brooklyn, NY


American Journal of Medical Case Reports. 2020, Vol. 8 No. 9, 262-267
DOI: 10.12691/ajmcr-8-9-2
Copyright © 2020 Science and Education Publishing

Cite this paper:
Mohammed Al-Sadawi, Amena Mohiuddin, Naseem Hossain, Shakil Shaikh, Alan Feit, Benjamin Ramalanjaona, Moro O. Salifu, Samy I. McFarlane. Management of ST-Elevation Myocardial Infarction in the COVID-19 Era: The Role of Thrombosis and Anticoagulation Strategy. American Journal of Medical Case Reports. 2020; 8(9):262-267. doi: 10.12691/ajmcr-8-9-2.

Correspondence to: Samy  I. McFarlane, Department of Medicine, SUNY Downstate health Sciences University, Brooklyn, NY. Email: smcfarlane@downstate.edu

Abstract

Cardiac manifestations of COVID-19 include myocarditis, demand ischemia, myocardial infarction and arrhythmias with prothrombotic state being a major underlying pathogenetic mechanism. In this report we present a case of a 57-year-old, otherwise healthy, woman who presented with chest pain and nausea and was found to have an inferior wall ST-elevation myocardial infarction (STEMI) in the setting of an active COVID-19 infection. Angiography revealed tortuous coronary arteries with a 100% right coronary artery occlusion with high thrombus burden and normal left coronary system. In light of the available literature regarding the pro-thrombotic effects of this novel corona virus, we continued full dose anticoagulation with Enoxaparin after the cardiac catheterization and transitioned to rivaroxaban and we also continued the patient on dual antiplatelet therapy prior to discharge.

Keywords