1Michigan State University, United States
American Journal of Medical Case Reports.
2020,
Vol. 8 No. 6, 148-149
DOI: 10.12691/ajmcr-8-6-3
Copyright © 2020 Science and Education PublishingCite this paper: Tyler Kemnic, James Choi, Samanjit Kandola, Khader Herzallah. New Diagnosis of Myasthenia Gravis Following Magnesium Replacement.
American Journal of Medical Case Reports. 2020; 8(6):148-149. doi: 10.12691/ajmcr-8-6-3.
Correspondence to: Tyler Kemnic, Michigan State University, United States. Email:
kemnicty@msu.eduAbstract
A 29-year-old female G2P2 with a past medical history of hyperthyroidism and depression was admitted for 2-months of progressively worsening weakness of her bilateral upper and lower extremities. Initial investigations were unremarkable, and the patient’s weakness improve the next morning. The patient was thought to have a Somatoform Disorder and was planned for home discharge, however on the day of discharge her magnesium was 1.2 mg/dL. After repletion, she developed seizure-like activity and respiratory failure, requiring mechanical ventilation and transfer to the ICU. In ICU, patient received another dose of replacement magnesium that caused another seizure, code blue and re-intubation. Subsequent lab work revealed reactive Acetylcholine receptor antibodies and subsequent chest imaging demonstrated thymoma, confirming a diagnosis of Myasthenia Gravis in Crisis. The patient improved following plasma exchange and was discharged home with outpatient follow up.
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