Sahar Mahmoud S. El Awady^1,, Azza El-Sayed Ali Hegazy², Taghreed Talaat³

Background: Vaccination means giving a vaccine to a child for activating immune system to resistant an infectious disease, by administration of a vaccine. These vaccines help to stimulate the body's own immune system to protect the children against subsequent diseases. Aim of this study is to evaluate the effect of instructional guidelines for mothers about children vaccination. Design: Quasi-experimental research design was used. Sample: purposive sample equal 375 mothers who having children and attending the routine immunization in centers. Settings: study was conducted at two Maternal-Child Health Centers (in-Helwan and Ezbat Elwalda) at, Ain-Helwan District and Helwan City, Cairo, Egypt. Tool: one tool used; Interview questionnaire sheet composed of 3 parts (Socio-demographiccharacteristics, mothers' knowledge & mothers' reported practice regarding children vaccination). Results: the mean age of mothers was 29.5±7.1 years. Mothers' total knowledge was improved post instructional guidelines than pre. Also, satisfactory reported practices of mothers regarding vaccination was 75% at the post than pre the instructional guidelines. Conclusion: the study denoted that there was an improvement of mothers' knowledge and reported practice after applying the instructional guidelinesthan before with statistically significant differences. Recommendations: provide mothers by health instructional guideline and vaccination booklets which include the importance of vaccination, side effects and how to manage its complications, obligatory vaccine schedule and non-obligatory vaccine schedule in centers.

vaccination, instructional guidelines, Maternal-Child Health Centers (MCH)