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Terdiman, J.P., Gruss, C.B., Heidelbaugh, J.J., Sultan, S., Falck-Ytter, Y.T. “American Gastroenterological Association Institute Guideline on the use of thiopurines, methotrexate and anti-TNF-alpha biologic drugs for induction and maintenance of remission in inflammatory Crohn’s disease.” Gastroenterology, 145: 1459-63. Dec.2013.

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Article

Adalimumab Induced Aseptic Meningitis and Focal Partial Seizures in Patient with Crohn’s Disease

1Graduate Medical Education, UnityPoint Health-Des Moines, Des Moines, United States

2UnityPoint Clinic Multi-Specialty-Infectious Disease, UnityPoint Health, Des Moines, United States


American Journal of Medical Case Reports. 2019, Vol. 7 No. 11, 289-291
DOI: 10.12691/ajmcr-7-11-7
Copyright © 2019 Science and Education Publishing

Cite this paper:
Corey S. Ellis, Hayden L. Smith, Lisa A Veach. Adalimumab Induced Aseptic Meningitis and Focal Partial Seizures in Patient with Crohn’s Disease. American Journal of Medical Case Reports. 2019; 7(11):289-291. doi: 10.12691/ajmcr-7-11-7.

Correspondence to: Hayden  L. Smith, Graduate Medical Education, UnityPoint Health-Des Moines, Des Moines, United States. Email: hayden.smith@unitypoint.org

Abstract

Tumor necrosis factor α inhibitors (TNFα-i) are a commonly prescribed class of medications for the treatment of inflammatory bowel disease. With the increasing use of this medication class, some uncommon adverse effects have been reported. We present a case of a young male recently prescribed adalimumab for Crohn’s disease who developed aseptic meningitis with associated focal partial seizures.

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