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Briani C, Doria A, Sarzi-Puttini P, Dalakas MC. Update on idiopathic inflammatory myo-Patties. Autoimmunity 2006; 39: 161-170.

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Article

Sprue-Like Intestinal Disease Complicated by Inclusion Body Myositis

1Department of Medicine (Gastoenterology), University of British Columbia, Vancouver, British Columbia, Canada


International Journal of Celiac Disease. 2019, Vol. 7 No. 2, 53-55
DOI: 10.12691/ijcd-7-2-5
Copyright © 2019 Science and Education Publishing

Cite this paper:
Hugh J. Freeman. Sprue-Like Intestinal Disease Complicated by Inclusion Body Myositis. International Journal of Celiac Disease. 2019; 7(2):53-55. doi: 10.12691/ijcd-7-2-5.

Correspondence to: Hugh  J. Freeman, Department of Medicine (Gastoenterology), University of British Columbia, Vancouver, British Columbia, Canada. Email: hugfree@shaw.ca

Abstract

A woman with long-standing weight loss and malabsorption demonstrated a severe sprue-like enteropathy. She insidiously developed persistent and progressive muscle weakness caused by inclusion body myositis, an uncommon muscle disorder. Treatment with a gluten-free diet, steroids, calcium, zinc and vitamin supplements, including empirical vitamin E resulted in weight gain, but failed to histologically improve her small intestinal mucosa or the muscle weakness which became profound. The myopathic process could reflect a co-existent autoimmune disorder, or, possibly a direct result of long-standing and superimposed nutrient deficits. An alternative explanation may be a hitherto unrecognized syndrome manifested as inclusion body myositis and a form of sprue-like enteropathy.

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