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De la Prada FJ, Prados A, Ramos R, Munar MA, Losada P, Morey A. Silent ischemic heart disease in patient with Wegener's necrotizing glomerulonephritis. Nefrologia. 2003; 23(6): 545-9.

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Article

Fatal Cardiac Involvement Revealing Granulomatosis with Polyangiitis

1Department of Internal Medicine, Military Hospital of Gabes, Gabes 6000, Tunisia

2Sfax Faculty of Medicine, University of Sfax, Sfax 3029, Tunisia

3Department of Forensic Medicine, Gabes Regional Hospital, Gabes 6000, Tunisia

4Department of Pathology, Fattouma Bourguiba Hospital, Monastir 5000, Tunisia


American Journal of Medical Case Reports. 2019, Vol. 7 No. 5, 90-93
DOI: 10.12691/ajmcr-7-5-4
Copyright © 2019 Science and Education Publishing

Cite this paper:
Salem Bouomrani, Karama Regaïeg, Nesrine Belgacem, Mouna Guermazi, Sami Krimi, Abdelfatteh Zakhama. Fatal Cardiac Involvement Revealing Granulomatosis with Polyangiitis. American Journal of Medical Case Reports. 2019; 7(5):90-93. doi: 10.12691/ajmcr-7-5-4.

Correspondence to: Salem  Bouomrani, Department of Internal Medicine, Military Hospital of Gabes, Gabes 6000, Tunisia. Email: salembouomrani@yahoo.fr

Abstract

Granulomatosis with polyangiitis (GPA), formerly known as Wegener's disease, is a rare necrotizing and granulomatous systemic vasculitis of small vessels. Cardiac involvement in GPA is unusual and the heart is part of the so-called "atypical" locations of this vasculitis. This complication is often little-known and overlooked by clinicians despite its severity and high mortality. Symptomatic acute myocardial infarction is an exceptional presentation of cardiac involvement associated to GPA. We report an original observation of fatal cardiac damage revealing GPA in a 50-year-old Tunisian man with no pathological medical history. The diagnosis was made on post-mortem examination.

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