1Organic Chemistry Department, Faculty of Chemistry, National Autonomous University of Mexico, Mexico City (CDMX), Mexico
World Journal of Organic Chemistry.
2019,
Vol. 7 No. 1, 1-4
DOI: 10.12691/wjoc-7-1-1
Copyright © 2019 Science and Education PublishingCite this paper: Francisco Sánchez-Viesca, Reina Gómez. On the Mechanism of the Froehde Reaction.
World Journal of Organic Chemistry. 2019; 7(1):1-4. doi: 10.12691/wjoc-7-1-1.
Correspondence to: Francisco Sánchez-Viesca, Organic Chemistry Department, Faculty of Chemistry, National Autonomous University of Mexico, Mexico City (CDMX), Mexico. Email:
franviesca@yahoo.comAbstract
Although the Froehde reaction is widely used for alkaloid preliminary identification, there is no reaction mechanism in order to explain the reaction course and the end products. We found there can be two redox steps and we provide a reaction mechanism for both of them and give two routes for the second reaction. The chemical deportment of the reagent, molybdic acid and its derivatives is also discussed.
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