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Hill ID, Dirks MH, Liptak GS, et al. Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr 2005; 40: 1-19.

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Article

False-negative IgA Anti-tissue Transglutaminase

1Department of Pediatrics, University Hospital of Setif; Setif 1 University, Algeria

2Genetic, Cardiovascular & Nutritional Diseases Laboratory; Setif-1 University, Algeria

3Central Laboratory, CAC Hospital of Setif; Setif-1 University, Algeria


International Journal of Celiac Disease. 2018, Vol. 6 No. 3, 87-88
DOI: 10.12691/ijcd-6-3-2
Copyright © 2019 Science and Education Publishing

Cite this paper:
Nada Boutrid, Hakim Rahmoune, Mounira Amrane. False-negative IgA Anti-tissue Transglutaminase. International Journal of Celiac Disease. 2018; 6(3):87-88. doi: 10.12691/ijcd-6-3-2.

Correspondence to: Nada  Boutrid, Department of Pediatrics, University Hospital of Setif; Setif 1 University, Algeria. Email: nadaboutrid@gmail.com

Abstract

The expanding knowledge about gluten-related autoimmunity led to a serology-based step-wised approach to diagnose celiac disease that might be misleading due to laboratory techniques. We present a rare case associating initial false-negative anti-transglutaminase IgA antibodies while CD was confirmed by IgG anti-transglutaminase and subsequent duodenal biopsy.

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