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Article

Marijuana Induced Type I Brugada Pattern: A Case Report

1Division of Cardiovascular Disease, Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, N.Y, U.S.A-11203

2Department of Internal Medicine, Wake Forest University, Baptist Health System, Winston-Salem, N.C., U.S.A-27101

3Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, N.Y, U.S.A-11203

4Northside Hospital, St. Petersburg, Florida, 33709


American Journal of Medical Case Reports. 2018, Vol. 6 No. 7, 134-136
DOI: 10.12691/ajmcr-6-7-4
Copyright © 2018 Science and Education Publishing

Cite this paper:
Pramod Theetha Kariyanna, Apoorva Jayarangaiah, Sudhanva Hegde, Jonathan D.Marmur, Perry Wengrofsky, Mena Yacoub, Michael Post, Samy I. McFarlane. Marijuana Induced Type I Brugada Pattern: A Case Report. American Journal of Medical Case Reports. 2018; 6(7):134-136. doi: 10.12691/ajmcr-6-7-4.

Correspondence to: Samy  I. McFarlane, Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, N.Y, U.S.A-11203. Email: Samy.mcfarlane@downstate.edu

Abstract

Marijuana is the most common drug of abuse in the United States. Marijuana acts on cannabinoid receptors CB1, CB2 and another distinct endothelial receptor. Marijuana is known to cause tachycardia, hypotension and hypertension. Various arrhythmias including atrial fibrillation, atrial flutter, II degree AV block, ventricular fibrillation, ventricular tachycardia, asystole and brugada pattern associated with marijuana use have been reported. We here present an interesting case of Type I Brugada pattern in electrocardiography (ECG) in a 36 year old healthy African American male who presented after smoking four joints. Urine toxicology test proved marijuana use. Acute coronary syndrome was ruled out, coronary angiogram revealed normal coronaries, 2D echocardiogram showed no evidence of structural heart disease. Upon resolution of Brugada pattern in ECG, procainamide challenge performed in electrophysiology laboratory did not induce Brugada pattern. Patient was asked to return to hospital if he developed fever that did not resolve with antipyretics. Further studies are required to to understand the effect of marijuana on cardiac ion channels.

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